KXStudio

KXStudio is a Debian,Ubuntu based distro, it is compatable with both repositories, as well as it's own based on Ubuntu 14.04.2 LTS. As the name implies it's main purpose is for professional audio and video production using a collection of applications and plugins.

KX Studio 14.04.2
An ISO release based on Ubuntu 14.04.2 LTS created 27/07/2015. , it is also available in a Live version. The live DVD contains an optimized version of KDE (4.11.1) and a low-latency kernel (version 3.8).

Applications
The list of pre-installed applications included on the ISO is impressive and very large.

Audio

 * Ardour3
 * Audacious
 * Audacity
 * Bristol
 * Cadence (and sub-tools)
 * Carla
 * Giada
 * Guitarix
 * Hydrogen
 * JAMin
 * Laborejo
 * LinuxSampler
 * LisaloQt
 * LMMS
 * Mixxx
 * MusE
 * Non-Mixer
 * Non-Sequencer
 * Non-Session-Manager
 * Non-Timeline
 * Petri-Foo
 * Phasex
 * Qsampler
 * Qsynth
 * Qtractor
 * Rakarrack
 * Renoise
 * Rosegarden
 * SEQ24
 * SooperLooper
 * Sunvox
 * VMPK
 * xjadeo
 * ZynAddSubFX

Other

 * Blender
 * Clementine
 * Digikam
 * Firefox
 * Gimp
 * GParted
 * Inkscape
 * KDE base (ark, dolphin, gwenview, k3b, etc)
 * Kdenlive
 * LibreOffice (Impress and Writer)
 * Muon
 * QdvdAuthor
 * SMPlayer
 * Synaptic
 * VLC
 * Wine

Complete information on applications can be found on KXstudios website

Desktop Environment
KXStudio uses KDE which integrates well with KXStudio applicattions, some instances of KDE Mint have been used and I myself have used KXStudio applications with an updated version of Ubuntu using Gnome as well as Linux Mint with Cinnamon both using a low-latency kernel. Although KXStudio comes packaged with KDE the applications and plugins can be installed (at times with some difficulty) from the repositories on any Ubuntu based system.